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. 2021 Jul 21;41(29):6328–6342. doi: 10.1523/JNEUROSCI.3027-20.2021

Table 1.

MNI coordinates and statistics for GLM1: effort-by-choice, choice, reward, effort, pupil rate, and RT modulation

Effect Brain region k t value p value MNI coordinates
x y z
Effort-by-choice (positive modulation) L superior medial gyrus 301 5.324 <0.0001 −3 18 45
L ACC 4.786 −6 27 27
Effort-by-choice (negative modulation) L postcentral gyrus 4085 6.382 <0.0001 −33 −42 57
R superior frontal gyrus 6.248 24 −6 66
R postcentral gyrus 6.242 30 −42 57
L middle temporal gyrus 147 4.688 0.009 −60 −30 −3
L middle temporal gyrus 4.151 −57 −51 −6
Choice (effortful > non-effortful) L middle frontal gyrus 146 4.749 0.02 −30 30 36
Choice (non-effortful > effortful) No suprathreshold clusters
Reward (positive modulation) L caudate nucleus 1320 7.417 <0.0001 −9 9 0
R IFG (p. orbitalis) 6.752 36 21 −9
L IFG (p. orbitalis) 5.662 −30 24 −3
R middle frontal gyrus 464 7.237 <0.0001 39 21 27
L inferior parietal lobule 1046 6.61 <0.0001 −36 −63 51
L precuneus 4.949 −3 −66 42
L middle occipital gyrus 4.948 −30 −78 27
R middle temporal gyrus 211 5.767 0.003 60 −30 −6
R middle temporal gyrus 3.781 57 −9 −18
R fusiform gyrus 900 5.57 <0.0001 24 −81 −9
L fusiform gyrus 5.044 −24 −78 −9
L cerebelum (Crus 2) 5.018 −12 −81 −27
L middle temporal gyrus 149 5.489 0.012 −60 −21 −15
L superior frontal gyrus 478 5.06 <0.0001 −21 36 48
L IFG (p. triangularis) 4.857 −39 21 24
L middle frontal gyrus 4.756 −36 12 57
L superior orbital gyrus 115 5.021 0.03 −30 51 3
R inferior parietal lobule 597 4.922 <0.0001 33 −72 24
R inferior parietal lobule 4.839 39 −60 48
R middle temporal gyrus 4.706 54 −48 12
L ACC 167 4.484 0.007 −6 42 12
Reward (negative modulation) No suprathreshold clusters
Effort (positive modulation) R rolandic operculum 151 5.503 0.008 48 3 12
L linual gyrus 365 4.482 <0.0001 −15 −84 3
L middle occipital gyrus 4.352 −30 −90 15
L calcarine gyrus 4.073 3 −75 15
R calcarine gyrus 117 4.313 0.022 30 −69 15
Effort (negative modulation) No suprathreshold clusters
Pupil rate (positive modulation) R precuneus 8334 7.993 <0.0001 6 −78 42
L calcarine gyrus 7.485 −3 −90 0
R superior frontal gyrus 1081 6.774 <0.0001 21 −9 69
R middle frontal gyrus 6.639 45 −9 57
L posterior-medial frontal 6.041 −18 −12 72
R temporal pole 307 6.500 <0.0001 54 15 −6
R insula lobe 4.806 36 9 12
L rectal gyrus 287 5.715 <0.0001 −15 12 −9
R caudate nucleus 4.519 9 6 3
R olfactory cortex 4.220 21 9 −15
L temporal pole 225 4.854 0.001 −57 9 −3
L IFG (p. opercularis) 4.283 −42 9 15
L IFG (p. orbitalis) 3.563 −30 27 −3
R superior temporal gyrus 138 4.600 0.013 57 −39 27
Pupil rate (negative modulation) L middle temporal gyrus 123 5.914 0.02 −51 −36 −3
L inferior temporal gyrus 3.581 −60 −12 −21
L angular gyrus 196 5.628 0.003 −54 −63 36
L superior medial gyrus 280 5.168 <0.0001 −6 48 45
R superior medial gyrus 4.652 3 30 60
L middle frontal gyrus 96 4.703 0.044 −33 24 51
RT (positive modulation) L cuneus 273 7.335 0.001 3 −93 24
R cuneus 6.818 6 −84 42
R paracentral lobule 6.657 6 −48 75
R IFG (p. orbitalis) 219 5.795 0.003 45 36 0
RT (negative modulation) R fusiform gyrus 11871 −14.006 <0.0001 36 −75 −9
L fusiform gyrus −12.751 −36 −69 −9
L middle occipital gyrus −11.346 −36 −87 6

All effects are from t tests; p values are at cluster-level FWE correction.