Table 1.
Demographics and Clinical Characteristics of Controls and Patients With Ischemic Optic Neuropathy
| Control (n = 9 Subjects) | NAION Acute (n = 5 Subjects) | NAION Chronic Unilateral (n = 6) | NAION Chronic Bilateral (n = 7) | |
|---|---|---|---|---|
| Age (y)a | 69 ± 7.3 | 52 ± 9.7 | 60 ± 14 | 64 ± 4.2 |
| Female, n (%) | 4 (44.4) | 0 (0) | 2 (33.3) | 2 (20) |
| Male, n (%) | 5 (55.6) | 5 (100) | 4 (66.7) | 8 (80) |
| Plasma immune profiling, n (%) | 9 (100) | 5 (100) | 6 (100) | 7 (100) |
| VF MD (dB), n (%)a | NA | −15.4 ± 9.0, 5 (100) | −26.1 ± 3.0, 6 (100) | −15.5 ± 11, 2 (28.6) |
| Hypertension, n (%) | 3 (33.3) | 2 (40) | 4 (66.7) | 5 (71.4) |
| Diabetes, n (%) | 1 (11.1) | 1 (20) | 2 (33.3) | 1 (14.3) |
| Hyperlipidemia, n (%) | 4 (44.4) | 2 (40) | 2 (33.3) | 5 (71.4) |
| Anemia, n (%) | 1 (11.1) | 0 (0) | 0 (0) | 1 (14.3) |
| Smoking, n (%) | 0 (0) | 0 (0) | 1 (16.7) | 1 (14.3) |
| OSA, n (%) | 0 (0) | 1 (20) | 5 (83.3) | 5 (71.4) |
| Hight altitude, n (%) | 0 (0) | 2 (40) | 1 (16.7) | 1 (14.3) |
| Had steroids, n (%) | 0 (0) | 3 (60) | 1 (16.7) | 0 (0) |
| Time between the first attack and blood collection (months)a | NA | 3.5 ± 11 | 39.5 ± 28.1 | 57.0 ± 82.3 |
| Time between the last attack and blood collection (months)a | NA | 1.0 ± 0.8 | 39.5 ± 28.1 | 54.0 ± 37.5 |
In total, 18 patients with NAION and 9 controls were enrolled.
a
Median ± standard deviation.