TABLE 2.
MNI coordinate | |||||||
---|---|---|---|---|---|---|---|
Region | Side | Voxel size | x | y | z | T | p * |
OCD patients > HCs | |||||||
Dorsolateral and medial prefrontal cortex, dorsal anterior cingulate cortex | L/R | 1,650 | 36 | 30 | −21 |
5.72 |
<.001 |
−3 | 0 | 54 | 5.58 | ||||
30 | 27 | 39 | 5.46 | ||||
Putamen, caudate | L | 151 | −27 | 12 | −9 | 4.71 | .006 |
−21 | 18 | −3 | 4.62 | ||||
−24 | 6 | 9 | 4.25 | ||||
Putamen, caudate | R | 107 | 27 | 15 | −6 | 4.76 | .016 |
18 | 15 | −9 | 4.10 | ||||
15 | 18 | 9 | 3.99 | ||||
Middle occipital gyrus | L | 319 | −45 | −81 | 18 | 6.11 | <.001 |
−54 | −72 | 18 | 5.07 | ||||
−36 | −93 | 9 | 4.49 | ||||
Inferior temporal gyrus | L | 302 | −51 | −30 | −30 | 6.19 | <.001 |
−45 | −36 | −30 | 6.00 | ||||
−42 | −45 | −39 | 5.07 | ||||
Middle temporal gyrus | L | 147 | −48 | 9 | −27 | 4.72 | .006 |
−45 | 24 | −15 | 4.42 | ||||
OCD patients < HCs | |||||||
Inferior parietal lobule | R | 523 | 30 | −60 | 45 | −8.24 | <.001 |
36 | −39 | 42 | −6.06 | ||||
30 | −78 | 21 | −4.89 | ||||
Inferior parietal lobule | L | 163 | −30 | −51 | 42 | −5.05 | .004 |
−48 | −36 | 51 | −4.81 | ||||
Cerebellum, fusiform gyrus | R | 2,116 | 39 | −72 | −30 | −7.70 | <.001 |
36 | −72 | −18 | −7.34 | ||||
21 | −87 | −21 | −6.86 | ||||
Cerebellum, fusiform gyrus | L | 330 | −39 | −75 | −18 | −5.30 | <.001 |
−24 | −87 | −15 | −4.40 | ||||
−27 | −63 | −18 | −4.39 | ||||
Posterior cingulate cortex | L/R | 176 | 12 | −33 | 45 | −4.20 | .004 |
−9 | −39 | 45 | −4.09 | ||||
3 | −45 | 51 | −3.56 | ||||
Insula | R | 89 | 39 | −12 | 12 | −4.25 | .031 |
36 | −27 | 12 | −4.15 | ||||
57 | −12 | 3 | −3.68 | ||||
Insula | L | 88 | −33 | −24 | 12 | −4.82 | .031 |
−39 | −9 | 0 | −3.69 |
Abbreviations: HCs, healthy control subjects; MNI, Montreal Neurological Institute; OCD, obsessive–compulsive disorder.