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. 2021 May 5;42(12):3792–3803. doi: 10.1002/hbm.25465

TABLE 2.

Significant differences in dALFF between drug‐naïve OCD patients and HCs

MNI coordinate
Region Side Voxel size x y z T p *
OCD patients > HCs
Dorsolateral and medial prefrontal cortex, dorsal anterior cingulate cortex L/R 1,650 36 30 −21

5.72

<.001

−3 0 54 5.58
30 27 39 5.46
Putamen, caudate L 151 −27 12 −9 4.71 .006
−21 18 −3 4.62
−24 6 9 4.25
Putamen, caudate R 107 27 15 −6 4.76 .016
18 15 −9 4.10
15 18 9 3.99
Middle occipital gyrus L 319 −45 −81 18 6.11 <.001
−54 −72 18 5.07
−36 −93 9 4.49
Inferior temporal gyrus L 302 −51 −30 −30 6.19 <.001
−45 −36 −30 6.00
−42 −45 −39 5.07
Middle temporal gyrus L 147 −48 9 −27 4.72 .006
−45 24 −15 4.42
OCD patients < HCs
Inferior parietal lobule R 523 30 −60 45 −8.24 <.001
36 −39 42 −6.06
30 −78 21 −4.89
Inferior parietal lobule L 163 −30 −51 42 −5.05 .004
−48 −36 51 −4.81
Cerebellum, fusiform gyrus R 2,116 39 −72 −30 −7.70 <.001
36 −72 −18 −7.34
21 −87 −21 −6.86
Cerebellum, fusiform gyrus L 330 −39 −75 −18 −5.30 <.001
−24 −87 −15 −4.40
−27 −63 −18 −4.39
Posterior cingulate cortex L/R 176 12 −33 45 −4.20 .004
−9 −39 45 −4.09
3 −45 51 −3.56
Insula R 89 39 −12 12 −4.25 .031
36 −27 12 −4.15
57 −12 3 −3.68
Insula L 88 −33 −24 12 −4.82 .031
−39 −9 0 −3.69

Abbreviations: HCs, healthy control subjects; MNI, Montreal Neurological Institute; OCD, obsessive–compulsive disorder.