. Author manuscript; available in PMC: 2022 Apr 1.

Published in final edited form as: J Addict Med. 2021 Apr 1;15(2):99–108. doi: 10.1097/ADM.0000000000000701

Table 2.

Number of deaths and person-years of observation among cohort of patients initially exposed to prescription opioid daily and non-daily for non-cancer, non-palliative care conditions among insured adults in the United States, 2010-2015 (N=4,054,417)

	Initial pattern of prescription opioid exposure

	Daily opioid supply	Non-daily opioid supply	Total
Number of deaths, n (%)	2,253 (2.02)	13,377 (0.34)	15,630 (0.39)
Person-years of observation	90,624.40	3,199,133.00	3,289,758.00
Crude mortality mate^a	2486.09	418.14	475.11
Crude IRR (95% CI)	5.95 (5.69, 6.22)
Crude RD (95% CI)^a	2067.94 (1965.04, 2170.84)

Abbreviations: IRR=incidence rate ratio, IRD=incidence rate difference, CI=confidence interval

Cases/100,000 person-years