Fig. 1. Maternal antibody response to coronavirus disease 2019 (COVID-19) mRNA vaccination. A. Number of women who produced no antibody response, produced an antibody response but did not demonstrate passive immunity to their neonates, or produced an antibody response and also demonstrated passive immunity to their neonates. Time 0 is day of maternal vaccination dose 1. The earliest detection of antibodies in neonates (passive immunity) was at 16 days post–maternal dose 1. The one mother–neonate dyad with no transfer of antibodies to the neonate was at 10.14 weeks from dose 1 and 6 weeks from dose 2. B. Maternal immunoglobulin (Ig)G levels vs weeks elapsed since maternal vaccination dose 1 for women who received only one dose of the vaccine (n=55). Time point 0 is day of vaccination dose 1. C. Maternal IgG levels vs weeks elapsed since maternal vaccination dose 2 for women who received both doses of the vaccine (n=67). Time point 0 is day of vaccination dose 2. All positive serology cutoffs were 1 (dashed line). The relationship between IgG antibody levels and time was studied using analysis of variance with Tukey post hoc. Statistical analysis was performed using R 3.6.3, RStudio 1.1.463. ns, not significant.

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