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Performance of the screening assays for detection of RBD mutations
| Screening assay result | No. of WGS results (n = 102) for spike mutationa: |
|||||
|---|---|---|---|---|---|---|
| L452R |
E484K |
N501Y |
||||
| Pos | Neg | Pos | Neg | Pos | Neg | |
| Pos | 8 | 0 | 12 | 0 | 46 | 0 |
| Neg | 0 | 94 | 0 | 90 | 0 | 56 |
For each comparison of positive (Pos) and negative (Neg) screening assay results and WGS results for each mutation shown, there was 100% positive percentage of agreement (PPA) and 100% negative percentage of agreement (NPA).
