Table 2.
Correlations Between Volume and Neuropsychological Performance in Regions that Differed in Primary Analyses
| CAN Users | Non-using Controls | Fisher’s z Comparison | |||||
|---|---|---|---|---|---|---|---|
| Neurocognitive Measure | Identified Region | r | p | r | p | Z | p |
| Whole Group | |||||||
| Ruff 2&7 | Left Superior Temporal1 | .02 | .91 | .33* | .046 | −1.32 | .19 |
| Males | |||||||
| PASAT | Right Paracentral2 | .43* | .046 | .39 | .11 | 0.15 | .88 |
| Ruff 2&7 | Left Lateral Orbitofrontal2 | −.03 | .89 | .49* | .04 | −1.65 | .10 |
| Left Inferior Temporal2 | .08 | .73 | .65* | .003 | −2.05* | .04 | |
| Left Precuneus2 | −.27 | .22 | .60* | .008 | −2.83* | .005 | |
| Left Caudal Middle Frontal2 | .44* | .036 | .48* | .046 | −0.13 | .89 | |
| Females | |||||||
| PASAT | Left Inferior Temporal4 | .65* | .016 | −.01 | .95 | 1.99* | .046 |
| Trails 4 | Left Precuneus3 | −.68* | .011 | −.52* | .02 | −0.63 | .53 |
| Right Superior Frontal4 | .54 | .057 | −.19 | .42 | 2.00* | .046 | |
Notes:
p<.05; CAN = Cannabis Users; PASAT = Paced Auditory Serial Addition Task; Fisher’s Z comparisons were run to determine whether correlation coefficients significantly differed between CAN and controls.
Region identified from Cannabis*VO2 analysis; controls demonstrated a more robust positive relationship between VO2 max and volume.
Regions identified from Cannabis*Sex analyses where CAN-using males had smaller volume compared to non-using males.
Regions identified from Cannabis*Sex analyses where CAN-using females had greater volume compared to non-using females.
Regions identified from Cannabis*Sex analyses where CAN-using females had smaller volume compared to non-using females.