Table 1.2. HFA PEFF score HFpEF diagnosis.
| DOMAIN | MAJOR CRITERIA (2 points) |
MINOR CRITERIA (1 point) |
|---|---|---|
| FUNCTIONAL | e’ septal < 7 or e’ lateral < 10 or E/e’ > 15 or RT velocity > 2.8 m/s (PSAP > 35 mmHg) |
E/e’: 9-14 or GLS < 16% |
| MORPHOLOGIC | LA Vol index > 34 mL/m2 or LVMI > 149/122 g/m2 (H/M) and RWT > 0.42 |
LA Vol index: 29 - 34 mL/m2 or LVMI > 115/95 g/m2 (H/M) or RWT > 0.42 or left ventricular wall thickness ≥ 12 mm |
| BIOMARKER (sinus rhythm) BIOMARKER (atrial fibrilation) |
NT-proBNP > 220 pg/mL or BNP > 80 pg/mL NT-proBNP > 660 pg/mL or BNP > 240 pg/mL |
NT-proBNP: 125 - 220 pg/mL or BNP 35 - 80 pg/mL NT-proBNP: 365 - 660 pg/mL or BNP: 105 - 240 pg/mL |
Adapted from Pieske B et al.7Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur J Heart Fail. 2020; 22:391-412.
BNP: B-type natriuretic peptide; GLS: global longitudinal systolic strain; LAVI: left atrial volume index; LV: left ventricular; m: men / w: women; NT-proBNP: N-terminal B-type natriuretic peptide; PW: posterior wall; RWT: relative wall thickness; TR velocity: tricuspid regurgitation velocity. BNP: B-type natriuretic peptide; GLS: global longitudinal systolic strain; LAVI: left atrial volume index; LV: left ventricular; m: men / w: women; NT-proBNP: N-terminal B-type natriuretic peptide; PW: posterior wall; RWT: relative wall thickness; TR velocity: tricuspid regurgitation velocity.