Table 1. – Infarction size, final echocardiogram, and morphometric analysis.
| Variable | SM (n = 19) | SOJ (n = 20) | IM (n = 9) | IOJ (n = 9) | p (I) | p (OJ) | p (I×OJ) |
|---|---|---|---|---|---|---|---|
| BW (g) | 454±47.9 | 480±56.3 | 443±66.6 | 462±25.9 | 0.338 | 0.135 | 0.852 |
| HR (bpm) | 290±30.9 | 296±34.9 | 268±26.7 | 324±30.0aB | 0.756 | 0.001 | 0.009 |
| LA/Ao | 1.32±0.09 | 1.21±0.09b | 1.78±0.21A | 1.42±0.18Ba | <0.001 | <0.001 | 0.003 |
| LVEDD/BW (mm/kg) | 15.9±1.31 | 15.0±1.79 | 22.1±2.70 | 20.2±2.10 | <0.001 | 0.019 | 0.398 |
| LVESD/BW (mm/kg) | 6.67±0.87 | 6.02±0.89 | 15.1±2.70 | 12.8±2.70 | <0.001 | 0.007 | 0.556 |
| LVMI (g/kg) | 1.63±0.22 | 1.56±0.27 | 2.62±0.60 | 2.36±0.36 | <0.001 | 0.124 | 0.640 |
| FAC (%) | 67.3±8.28 | 67.4±8.27 | 34.5±8.28 | 36.6±8.28 | <0.001 | 0.661 | 0.707 |
| E wave (ms) | 79.7±11.3 | 81.4±7.16 | 89.1±10.8 | 80.7±19.2 | 0.204 | 0.325 | 0.139 |
| A wave (ms) | 49.9±8.28 | 52.6±7.16 | 42.5±16.5 | 62.7±24.9a | 0.730 | 0.004 | 0.025 |
| S´ mean (cm/s) | 5.78±0.04 | 5.82±0.31 | 4.60±0.30 | 5.01±0.3 | <0.001 | 0.028 | 0.078 |
| E´ mean (cm/s) | 5.62±0.44 | 5.82±0.45 | 4.23±0.60 | 4.77±0.60 | <0.001 | 0.054 | 0.357 |
| A´ mean (cm/s) | 3.67±0.44 | 4.02±0.45 | 4.54±0.90 | 5.55±1.20 | 0.058 | 0.058 | 0.28 |
| E/E´ ratio | 13.7±3.49 | 14.1±1.79 | 21.3±3.30A | 16.9±2.40Ba | <0.001 | 0.002 | 0.003 |
| LVW/BW (mg/g) | 1.85±0.13 | 1.93±0.27 | 2.13±0.42 | 2.10±0.15 | 0.005 | 0.550 | 0.822 |
| RVW/BW (mg/g) | 0.46±0.09 | 0.43±0.05 | 0.65±0.24 | 0.59±0.27 | <0.001 | 0.294 | 0.776 |
Data are expressed as mean ± standard deviation. n: numbers of animals included in each experimental group. SM: sham animals that received maltodextrin; SOJ: sham animals that received orange juice; IM: infarcted animals that received maltodextrin; IOJ: infarcted animals that received orange juice. BW: body weight; HR: heart rate; LA: left atrial diameter; Ao: aorta diameter; LVEDD: left ventricular end-diastolic diameter; LVESD: left ventricular end-systolic diameter; LVMI: left ventricular mass index (left ventricular mass/BW); FAC: fractional area change; E wave: early diastolic mitral inflow velocity; A wave: late diastolic mitral inflow velocity; S´ mean: mean of systolic annular mitral velocity septal and lateral; A´ and E´ mean: mean of diastolic annular mitral velocity septal and lateral (E´: early and A: late); LVW: left ventricular weight; RVW: right ventricular weight. pI: p value for the effect of infarction. pOJ: p value of the effect of orange juice intake. pIxOJ: p value of interaction. Bold numbers represent statistically significant effects;a: IM≠IOJ;b: SM≠SOJ;A: SM≠IM eB:SOJ≠IOJ.