Table 2. – Oxidative stress and inflammatory markers.
| Variable | SM (n = 8) | SOJ (n = 8) | IM (n = 4) | IOJ (n = 4) | p (I) | p (OJ) | p (I×OJ) |
|---|---|---|---|---|---|---|---|
| LH (nmol/g) | 209±28.3 | 215±28.3 | 256±28.0 | 277±26.0 | <0.001 | 0.293 | 0.573 |
| Catalase (µmol/g) | 64.4±6.79 | 61.8±7.07 | 55.4±7.00 | 58.1±7.60 | 0.056 | 0.993 | 0.404 |
| SOD (nmol/mg) | 12.9±2.83 | 13.5±2.83 | 18.7±1.80 | 17.1±1.40 | <0.001 | 0.639 | 0.355 |
| GSH-px activity (nmol/mg) | 62.5±6.51 | 50.2±7.07 | 58.0±7.00 | 45.3±6.00 | 0.134 | <0.001 | 0.951 |
| GSH-px expression (arbitrary unit) | 7.56±7.39 | 7.62±10.8 | 6.63±5.82 | 6.37±3.78 | 0.600 | 0.649 | 0.546 |
| IL-10 (pg/mg) | 23.9±7.92 | 39.6±13.0b | 42.0±9.60A | 34.1±7.60 | 0.135 | 0.352 | 0.008 |
| IFN-γ (pg/mg) | 7.1±2.26 | 13.2±3.96b | 17.7±6.80A | 11.2±2.00a | 0.037 | 0.928 | 0.003 |
| NF-κB (arbitrary unit) | 7.03±11.0 | 4.61±4.98 | 3.40±3.12 | 6.80±4.00 | 0.942 | 0.330 | 0.266 |
| p NF-κB (arbitrary unit) | 5.40±10.2 | 3.18±2.40 | 3.28±3.12 | 5.22±3.34 | 0.587 | 0.084 | 0.980 |
| Sirt 1 (arbitrary unit) | 1.81±0.82 | 2.34±1.41 | 2.42±1.44 | 1.65±0.56 | 0.925 | 0.813 | 0.203 |
Data are expressed as mean ± standard deviation. n: numbers of animals included in each experimental group. SM: sham animals that received maltodextrin; SOJ: sham animals that received orange juice; IM: infarcted animals that received maltodextrin; IOJ: infarcted animals that received orange juice. LH: lipid hydroperoxide; SOD: superoxide dismutase; GSH-px: glutathione peroxidase; IL-10: interleukin-10; INF-γ: interferon- γ; NF-κB: nuclear factor–κB total and phosphorylated (p NF-κB); Sirt 1: sirtuin 1. pI: p value for the effect of infarction. pOJ: p value of orange juice intake effect. pIxOJ: p value of interaction.Bold numbers represent statistically significant effects. a : IM≠IOJ; b : SM≠SOJ; A : SM≠IM e B: SOJ≠IOJ.