Table 2. – Association of plasma NT-proBNP levels with clinical variables.

Variables	Univariate		Multivariate
	r value	p value	Standard β value	p value	95% CI
sex	0.003	0.926
Age	0.178	<0.001	0.082	0.019	0.002 to 0.023
CHD	0.136	<0.001	-0.004	0.913	-0.104 to 0.093
HT	0.072	0.053	0.011	0.753	-0.075 to 0.104
AF	0.310	<0.001	0.218	0.000	0.213 to 0.414
DM	0.047	0.202
eGFR	-0.240	<0.001	-0.131	0.003	-0.005 to 0.000
sCr	0.285	<0.001	0.192	0.001	0.001 to 0.003
BUN	0.325	<0.001	0.112	0.010	0.004 to 0.028
TC	-0.162	<0.001	0.058	0.485	-0.067 to 0.142
LDL-C	-0.173	<0.001	-0.050	0.535	-0.161 to 0.084
HDL-C	0.026	0.495
TG	-0.111	0.004	-0.088	0.018	-0.107 to -0.010
Hb	-0.293	<0.001	-0.121	0.002	-0.006 to -0.001
ALB	-0.287	<0.001	-0.137	0.000	-0.033 to -0.009
LVEF	-0.261	<0.001	-0.179	0.000	-0.029 to -0.013
LAD	0.292	<0.001	0.179	0.000	0.015 to 0.036
LVMI	0.163	<0.001	0.006	0.865	-0.001 to 0.001
BMI	-0.170	<0.001	-0.111	0.005	-0.032 to -0.006
Antiplatelet drug	0.026	0.478
statins	0.007	0.848
CCB	-0.056	0.136
ARB	-0.047	0.204
ACEI	0.074	0.046	0.057	0.088	-0.014 to 0.205
ACEI/ARB	0.005	0.883
Beta-blocker	0.172	<0.001	0.124	0.000	0.066 to 0.219
SBP	-0.007	0.860
DBP	-0.110	0.003	0.000	0.992	-0.006 to 0.005
MBP	-0.075	0.042
PP	0.065	0.080	0.065	0.064	0.000 to 0.007

CHD: coronary heart disease; HT: hypertension; DM: diabetes mellitus; AF: atrial fibrillation; BMI: body mass index; NT-proBNP: N-terminal pro-brain natriuretic peptide; eGFR: estimated glomerular filtration rate; sCr: serum creatinine; BUN: blood urea nitrogen; TC: total cholesterols; TG: triglyceride; LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol; Hb: hemoglobin; ALB: plasma albumin; LVEF: left ventricular ejection fraction; LAD: left atrial diameter; LVMI: left ventricular mass index; CCB: calcium channel blocker; ACEI: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor antagonists; SBP: systolic blood pressure; DBP: diastolic blood pressure; MBP: mean blood pressure; PP: pulse pressure.