Table 1. – Baseline characteristics of patients and comparison of groups defined by baseline MR dysfunction (n = 795).
| Characteristic | Whole population (n = 795) | According to baseline MR dysfunction | p value* | |
|---|---|---|---|---|
|
| ||||
| Absent/mild (n = 642) | Moderate/severe (n = 153) | |||
| Age (years) | 81.5 ± 7.3 | 81.2 ± 7.5 | 83.1 ± 6.6 | 0.002 |
| Male | 389 (48.9) | 313 (48.8) | 76 (49.7) | 0.838 |
| Coronary artery disease | 465 (58.4) | 375 (58.4) | 90 (58.8) | 0.926 |
| Previous myocardial infarction | 117 (14.7) | 99 (15.4) | 18 (11.8) | 0.251 |
| Peripheral vascular disease | 136 (17.1) | 118 (18.4) | 18 (11.8) | 0.051 |
| Stroke/TIA | 63 (7.9) | 50 (7.8) | 13 (8.5) | 0.771 |
| Diabetes | 253 (31.8) | 206 (32.1) | 47 (30.7) | 0.744 |
| Systemic arterial hypertension | 601 (75.5) | 484 (75.4) | 117 (76.5) | 0.780 |
| Renal failure | 615 (77,3) | 485 (75.5) | 130 (85.0) | 0.012 |
| Preprocedural pacemaker | 81 (10.2) | 57 (8.8) | 24 (15.6) | 0.012 |
| Hemoglobin (mg/dl) | 11.8 ± 1.7 | 11.8 ± 1.8 | 11.5 ± 1.6 | 0.045 |
| Pulmonary hypertension | 176 (22.1) | 133 (20.7) | 43 (28.1) | 0.048 |
| NYHA functional class III or IV | 648 (81.5) | 511 (79.6) | 137 (89.5) | 0.004 |
| Atrial fibrillation | 106 (13.3) | 78 (12.3) | 28 (18.5) | 0.044 |
| EuroScore mortality | 16 ( 17.6) | 15.2 (16.6) | 21.1 (17.5) | 0.001 |
| STS score mortality | 7.2 (10.5) | 6.6 (9.9) | 10.9 (12) | <0.001 |
| Moderate/severe baseline aortic regurgitation | 95 (11.9) | 60(10,9) | 35(23.0) | <0,001 |
| Previous balloon aortic valvuloplasty | 50 (6,2) | 36 (5,6) | 14 (9,2) | 0,105 |
| Baseline EF (%) | 58.7 ± 14.9 | 60.1 ± 14.4 | 53.2 ± 16.0 | <0.001 |
| Baseline LV diastolic diameter (mm) | 50.8 ± 9.4 | 50.2 ± 8.8 | 53.4 ± 10.3 | 0.001 |
| Baseline aortic valve area (cm2) | 0.66 ± 0.19 | 0.67 ± 0.19 | 0.63 ± 0.19 | 0.016 |
| Baseline mean aortic gradient (mmHg) | 49.3 ± 16.0 | 50.1 ± 15.7 | 46.3 ± 16.5 | 0.010 |
| Baseline peak aortic gradient (mmHg) | 81.0 ± 24.8 | 82.3 ± 24.6 | 76.0 ± 25.0 | 0.005 |
Results described by frequency (percentage), mean ± standard deviation or median (interquartile range). *Student t test for independent samples, non-parametric Mann-Whitney test (quantitative variables), or chi-square test (categorical variables), p < 0.05. EF: ejection fraction, LV: left ventricle, MR: mitral regurgitation, NYHA: New York Heart Association, STS: Society of Thoracic Surgeons, TIA: transient ischemic attack.