Table 3.
Performance when requiring reactivity towards two specific antigens out of Spike‐f, S1 or NC‐C, or reactivity towards two out of the three antigens, based on the analysis of 331 positive and 2090 negative controls
| Antigen | Host | Positive controls | Negative controls | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Sensitivity [%] | 95% CI | Positive result | Negative result | Specificity [%] | 95% CI | Positive result | Negative result | ||
|
Spike‐f NC‐C |
HEK E. coli |
99.7 | 98.3–100 | 330 | 1 | 100 | 99.8–100 | 0 | 2090 |
|
S1 NC‐C |
CHO E. coli |
99.1 | 97.4–99.8 | 328 | 3 | 99.9 | 99.7–100 | 2 | 2088 |
|
Spike‐f S1 |
HEK CHO |
99.1 | 97.4–99.8 | 328 | 3 | 99.5 | 99.1–99.8 | 10 | 2080 |
|
Spike‐f |
HEK |
||||||||
|
S1 |
CHO |
99.7 | 98.3–100 | 330 | 1 | 99.4 | 99.0–99.7 | 12 | 2078 |
|
NC‐C |
E. coli |
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