Table 2. Factors associated with neovascularization in the fellow eye of patients presenting with unilateral type 3 neovascularization.
Risk factors | Fellow eye NV(+) n = 49 | Fellow eye NV(-) n = 44 | p-value |
---|---|---|---|
Age, years | 76.9 ± 5.5 | 77.6 ± 6.5 | 0.606† |
Sex, male (%) | 9 (18.4%) | 9 (20.5%) | 0.799* |
Follow-up duration, months | 68.4 ± 31.4 | 63.5 ± 31.0 | 0.458† |
Diabetes mellitus, no.(%) | 12 (24.5%) | 4 (9.1%) | 0.091 ‡ |
Hypertension, no.(%) | 19 (38.8%) | 13 (30.0%) | 0.350* |
Large soft drusen of the fellow eye, no. (%) | 41 (83.7%) | 16 (36.46%) | <0.001* |
Reticular pseudodrusen of the fellow eye, no. (%) | 33 (67.3%) | 18 (40.9%) | 0.017* |
Subfoveal choroidal thickness of the fellow eye, μm | 156.9 ± 53.4 | 167.9 ± 78.3 | 0.176† |
Choroidal vascular index of the fellow eye, % | 60.7 ± 2.0 | 61.7 ± 2.5 | 0.047† |
Type 3 neovascularization stage, no. (%) | 0.980* | ||
1 | 11 (22.4%) | 10 (22.7%) | |
2 | 17 (34.7%) | 16 (36.4%) | |
3 | 21 (42.9%) | 18 (40.9%) |
All continuous data are presented as means ± standard deviations.
† p-value by independent t-test,
* p-value by chi-square test,
‡ p-value by Fisher’s exact test,
NV, neovascularization.