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. 2020 May 30;7(8):1306–1318. doi: 10.1093/nsr/nwaa099

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© The Author(s) 2020. Published by Oxford University Press on behalf of China Science Publishing & Media Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Cell type annotation of tumor microenvironment cells and malignant cells. (A) Heatmap shows marker genes of sub-clusters of tumor microenvironment cells. Pie plot at the top shows cell ratio of LGG/GBM/metastasis samples. Cells in clusters marked with IFI show interferon-induced property. (B) Cells clustered by TCGA 4 classification genes. Heatmap at the bottom shows the average expression value of five gene-sets marked in the left color bar. (C) Tumor cell subtype mapped in t-SNE coordinates.