Table 1.

Structural Retinal Changes with Aging

Retinal Component	Change from Aging
Thickness	Decreases, especially the Inner Nuclear Layer.16,17
Macular Blood Flow	Reduced by 20% on average.20
Microglia	Less motile, slower response time to injury, denser, with a smaller dendritic arbor.23
RPE	Decreased melanin production, increased lipofuscin accumulation.23,24
Müller Cells	More susceptible to oxidative stress.20,24