Table 2.

A list of known and novel mutations detected by whole genome sequencing in genes involved in antifungal resistance in the C. albicans clinical isolate CA77

Genes	Mutations	Mutation description	References
ERG11	D116E	Known mutation but not previously involved in antifungal resistance	[36]
ERG24	H46Q – I88V – A307V	Novel mutations	–
ERG251	R310Q	Novel mutation	–
UPC2	I142S	Known mutation but not previously involved in antifungal resistance	[36]
CDR1	T842S – T950S – E948P – I916V	Known mutations but not previously involved in antifungal resistance	[37]
MRR2	V451A – S480P	Known mutations but not previously involved in antifungal resistance	[38]
FKS1	P1838I	Novel mutation	–
	T1886S	Known mutation but not previously involved in antifungal resistance	[36]
GLS1	T181I – I340V – Q459R – M679I – T938M	Novel mutations	–