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. 2021 Jul 5;11:640892. doi: 10.3389/fonc.2021.640892

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Copyright © 2021 Wang, Wang, He, Li and Song

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meier survival curves for overall survival (OS) (A), progression-free survival (PFS) (B), locoregional failure-free survival (LRFS) (C) and distant metastasis-free survival (DMFS) (D) of the 37 ONB patients with frontal lobe invasion according to the cervical lymph node metastasis at initial diagnosis. Log-rank tests show that ONB patients without lymph node metastasis have superior 3-year OS (p = 0.004), PFS (p = 0.003), LRFS (p = 0.015), and DMFS (p = 0.004) compared with those having cervical lymph node metastasis.