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. 2021 Jul 5;11:640892. doi: 10.3389/fonc.2021.640892

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Copyright © 2021 Wang, Wang, He, Li and Song

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meier survival curves for overall survival (OS) (A) and progression-free survival (PFS) (B) of the 37 ONB patients with frontal lobe invasion stratified by IR plus S vs. IR. Log-rank tests show that the combination of IR and S has better OS (p = 0.001) and PFS (p = 0.001) than IR alone. Kaplan–Meier survival curves for OS (C) and PFS (D) of the 37 ONB patients according to chemotherapy (without Chemo vs. with Chemo). Log-rank test shows no significant differences between the two groups. IR, irradiation therapy; S, surgery; Chemo, chemotherapy.