Table 2. C–H Iodination of Nimesulide^a.

electrophilic C–H iodination method	yieldb
I2 (2.0 equiv) + AgOMs (2.0 equiv) in 0.2 M MeCN	92%c
NIS (1 equiv) in 0.2 M HFIP	<1%

^aReactions were carried out on a 0.1 mmol scale.

^bYields determined by ¹H NMR spectroscopy with dibromomethane as an internal standard.

^cIsolated yield.