Table I.
PCOS diagnosis | |||||
---|---|---|---|---|---|
Prior diagnosis (N = 56) | Study diagnosis (N = 64) |
Prior vs Study
P-valuea |
No PCOS (N = 854) | Three-group comparison P-valuea | |
Age at follow-up | |||||
Median (IQR) | 30.6 (30.0–31.4) | 30.2 (29.9–30.8) | 0.20 | 30.6 (30.0–31.5) | 0.02 |
Sociodemographics | n (%) | n (%) | n (%) | ||
Educational attainment | 0.47 | 0.50 | |||
Some high school | 19 (33.9) | 24 (37.5) | 253 (29.6) | ||
Completed high school | 26 (46.4) | 23 (35.9) | 377 (44.2) | ||
University | 11 (19.6) | 17 (26.6) | 224 (26.2) | ||
Socio-economic index for area | 0.75 | 0.21 | |||
Quartile 1 (most disadvantaged) | 19 (33.9) | 17 (26.6) | 188 (22.0) | ||
Quartile 2 | 14 (25.0) | 20 (31.3) | 212 (24.8) | ||
Quartile 3 | 11 (19.6) | 11 (17.2) | 236 (27.6) | ||
Quartile 4 (least disadvantaged) | 12 (21.4) | 16 (25.0) | 218 (25.5) | ||
Ethnicity | 0.63 | 0.23 | |||
Asian | 0 (0.0) | 0 (0.0) | 9 (1.1) | ||
European | 53 (94.6) | 59 (92.2) | 809 (94.7) | ||
Pacific/aboriginal | 3 (5.4) | 4 (6.3) | 18 (2.1) | ||
Other/unknown | 0 (0.0) | 1 (1.6) | 18 (2.1) | ||
Health risk factors | n (%) | n (%) | n (%) | ||
Current BMIb | 0.67 | <0.001 | |||
Underweight/normal (<25) | 14 (25.5) | 15 (23.8) | 412 (48.9) | ||
Overweight (25–<30) | 14 (25.5) | 13 (20.6) | 232 (27.5) | ||
Obese 1 (30–<35) | 13 (23.6) | 11 (17.5) | 109 (12.9) | ||
Obese 2/3 (35+) | 14 (25.5) | 24 (38.1) | 90 (10.7) | ||
Current smoker | 21 (37.5) | 19 (29.7) | 0.37 | 230 (26.9) | 0.22 |
Current alcoholic drinks per day | |||||
0 | 14 (25.0) | 11 (17.2) | 0.53 | 147 (17.4) | 0.09 |
1 | 16 (28.6) | 18 (28.1) | 344 (40.6) | ||
≥2 | 26 (46.4) | 35 (54.7) | 356 (42.0) | ||
Medical conditions (ever diagnosed) | |||||
High blood pressure | 10 (17.9) | 5 (7.8) | 0.10 | 43 (5.0) | <0.001 |
High cholesterol | 9 (16.1) | 6 (9.4) | 0.27 | 44 (5.2) | 0.002 |
High blood sugar | 6 (10.7) | 4 (6.3) | 0.38 | 14 (1.6) | <0.001 |
Diabetes | 0 (0.0) | 1 (1.6) | 0.35 | 5 (0.6) | 0.52 |
Depression | 18 (32.1) | 20 (31.3) | 0.92 | 175 (20.5) | 0.021 |
Asthma | 21 (37.5) | 17 (26.6) | 0.20 | 209 (24.0) | 0.092 |
Thyroid condition | 3 (5.4) | 5 (7.8) | 0.59 | 28 (3.3) | 0.14 |
Clinical depression from symptom scorec | 26 (51.0) | 29 (50.0) | 0.92 | 235 (29.2) | <0.001 |
Current medication use | |||||
Any medication | 27 (48.2) | 20 (31.3) | 0.06 | 226 (26.5) | 0.002 |
Metformin | 5 (8.9) | 0 (0.0) | 0.02 | 1 (0.1) | <0.001 |
Antidepressant | 4 (7.4) | 3 (4.7) | 0.57 | 38 (4.5) | 0.65 |
Asthma medications | 4 (7.1) | 2 (3.1) | 0.31 | 39 (4.6) | 0.57 |
Thyroxine | 0 (0.0) | 3 (4.7) | 0.11 | 9 (1.1) | 0.03 |
Pearson’s Chi2 test.
BMI data was missing for 13 women (Prior PCOS = 1, Study PCOS = 1, No PCOS = 11).
Center for Epidemiological Studies Depression Scale (CES-D) > 16; score missing for 60 women (Prior PCOS = 5, Study PCOS = 6, No PCOS = 49).
IQR, interquartile range; PCOS, polycystic ovary syndrome.