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. 2021 May 8;36(8):2275–2284. doi: 10.1093/humrep/deab101

Table I.

Demographic, lifestyle and health characteristics of women by polycystic ovary syndrome diagnosis group.

PCOS diagnosis
Prior diagnosis (N = 56) Study diagnosis (N = 64) Prior vs Study
P-valuea
No PCOS (N = 854) Three-group comparison P-valuea
Age at follow-up
 Median (IQR) 30.6 (30.0–31.4) 30.2 (29.9–30.8) 0.20 30.6 (30.0–31.5) 0.02
Sociodemographics n (%) n (%) n (%)
 Educational attainment 0.47 0.50
  Some high school 19 (33.9) 24 (37.5) 253 (29.6)
  Completed high school 26 (46.4) 23 (35.9) 377 (44.2)
  University 11 (19.6) 17 (26.6) 224 (26.2)
 Socio-economic index for area 0.75 0.21
  Quartile 1 (most disadvantaged) 19 (33.9) 17 (26.6) 188 (22.0)
  Quartile 2 14 (25.0) 20 (31.3) 212 (24.8)
  Quartile 3 11 (19.6) 11 (17.2) 236 (27.6)
  Quartile 4 (least disadvantaged) 12 (21.4) 16 (25.0) 218 (25.5)
 Ethnicity 0.63 0.23
  Asian 0 (0.0) 0 (0.0) 9 (1.1)
  European 53 (94.6) 59 (92.2) 809 (94.7)
  Pacific/aboriginal 3 (5.4) 4 (6.3) 18 (2.1)
  Other/unknown 0 (0.0) 1 (1.6) 18 (2.1)
Health risk factors n (%) n (%) n (%)
 Current BMIb 0.67 <0.001
  Underweight/normal (<25) 14 (25.5) 15 (23.8) 412 (48.9)
  Overweight (25–<30) 14 (25.5) 13 (20.6) 232 (27.5)
  Obese 1 (30–<35) 13 (23.6) 11 (17.5) 109 (12.9)
  Obese 2/3 (35+) 14 (25.5) 24 (38.1) 90 (10.7)
 Current smoker 21 (37.5) 19 (29.7) 0.37 230 (26.9) 0.22
 Current alcoholic drinks per day
  0 14 (25.0) 11 (17.2) 0.53 147 (17.4) 0.09
  1 16 (28.6) 18 (28.1) 344 (40.6)
  ≥2 26 (46.4) 35 (54.7) 356 (42.0)
 Medical conditions (ever diagnosed)
  High blood pressure 10 (17.9) 5 (7.8) 0.10 43 (5.0) <0.001
  High cholesterol 9 (16.1) 6 (9.4) 0.27 44 (5.2) 0.002
  High blood sugar 6 (10.7) 4 (6.3) 0.38 14 (1.6) <0.001
  Diabetes 0 (0.0) 1 (1.6) 0.35 5 (0.6) 0.52
  Depression 18 (32.1) 20 (31.3) 0.92 175 (20.5) 0.021
  Asthma 21 (37.5) 17 (26.6) 0.20 209 (24.0) 0.092
  Thyroid condition 3 (5.4) 5 (7.8) 0.59 28 (3.3) 0.14
  Clinical depression from symptom scorec 26 (51.0) 29 (50.0) 0.92 235 (29.2) <0.001
 Current medication use
  Any medication 27 (48.2) 20 (31.3) 0.06 226 (26.5) 0.002
  Metformin 5 (8.9) 0 (0.0) 0.02 1 (0.1) <0.001
  Antidepressant 4 (7.4) 3 (4.7) 0.57 38 (4.5) 0.65
  Asthma medications 4 (7.1) 2 (3.1) 0.31 39 (4.6) 0.57
  Thyroxine 0 (0.0) 3 (4.7) 0.11 9 (1.1) 0.03
a

Pearson’s Chi2 test.

b

BMI data was missing for 13 women (Prior PCOS = 1, Study PCOS = 1, No PCOS = 11).

c

Center for Epidemiological Studies Depression Scale (CES-D) > 16; score missing for 60 women (Prior PCOS = 5, Study PCOS = 6, No PCOS = 49).

IQR, interquartile range; PCOS, polycystic ovary syndrome.