. 2021 Jun 16;23(13):4986–4990. doi: 10.1021/acs.orglett.1c01403

Table 1. Effect of the Variation of the Aziridine and Allyl Reagent.

entry	R	reagent	product	yield (%)
1^a,^b	CO₂^tBu	allyl acetate	12a	87
2^b,^c	COMe	allyl acetate	12b	56^d
3^b,^c	CONHEt	allyl acetate	12c	60^d
4^a,^b	CN	allyl acetate	12d	0^e
5^d	CO₂^tBu	none	13a	83
6^a	COMe	none	13b	82
7^a	CONHEt	none	13c	44
8^a	CN	none	13d	0^e
9^a,^f	CO₂^tBu	none	13a	0
10^a,^g	CO₂^tBu	none	13a	0

Reaction performed at 70 °C.

Performed in the presence of 1.3 equiv of K₂CO₃.

Reaction performed at 30 °C.

Yield determined by ¹H NMR using 1,3,5-trimethoxybenzene as the internal standard.

Slow conversion to retro-ene product 3 was observed.⁹

Performed using Pd(PPh₃)₄.

Performed using Pd₂(dba)₃/PPh₃.