Table II.

Results of the epigenome-wide association study meta-analysis (CpG sites at P_FDR < 0.05).

				Meta-analysis					Study-specific results
									ARIES			MoBa			ALSPAC-MAR
CpG site	Gene	Chromosome	Position	Beta	SE	P-value	P FDR	P Bonferroni	Beta	SE	P-value	Beta	SE	P-value	Beta	SE	P-value
cg24051276		8	145561488	0.23	0.04	6.69 × 10−9	0.003	0.003	0.46	0.06	1.47 × 10−12	0.21	0.12	0.103	0.06	0.05	0.267
cg00012522	ARRDC4	15	98503952	0.47	0.08	2.94 × 10−8	0.007	0.014	0.73	0.12	2.03 × 10−09	0.14	0.13	0.297	0.50	0.25	0.047
cg17855264		15	37180636	0.31	0.06	5.44 × 10−8	0.007	0.026	0.74	0.09	3.95 × 10−15	0.21	0.14	0.117	−0.04	0.09	0.645
cg17132421	ARRDC4	15	98503947	0.30	0.06	5.86 × 10−8	0.007	0.028	0.38	0.07	3.28 × 10−08	0.07	0.11	0.514	0.31	0.18	0.089
cg18529845	SRD5A2	2	31806042	0.41	0.08	3.41 × 10−07	0.033	0.164	0.67	0.10	6.25 × 10−12	−0.31	0.17	0.069	0.08	0.31	0.807

Beta regression coefficients are reported as percent difference in methylation between groups.

FDR, False discovery Rate; ALSPAC, Avon Longitudinal Study of Parents and Children; ARIES, Accessible Resource for Integrated Epigenomics Studies; MAR, Medically Assisted Reproduction: MoBa, Norwegian Mother, Father, and Child Birth Cohort.