Figure 5.

Enrichment overrepresentation analysis results of UF-EVs transcriptomes: GOSt multiquery plot of Manhattan. The top n = 200 most abundant transcripts excluding rRNA were selected and tested against BP, MF, CC, Reactome and Wikipathway collections, among others. The most significant results (FDR < 0.05) are highlighted. Y-axis represents Benjamini corrected P-values (−log₁₀) and X-axis represents the functional terms grouped and color coded by data source. The position of the terms in the frames is fixed and the terms of the same branch (Gene Ontology-GO) are close to each other (short link to full g:Profiler results: https://biit.cs.ut.ee/gplink/l/opagQqFsQz). BP, biological process; CC, cellular component; FDR, false discovery rate; G:OSt, Gene ontology Statistics; MF, molecular function; UF-EVs, uterine fluid-derived extracellular vesicles.