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. 2021 Jul 19;16(7):e0254998. doi: 10.1371/journal.pone.0254998

Table 1. Proportion of goats with genotypes associated with prolonged incubation period or resistant genotypes, by codon along with significance test results for overall effect of each breakout variable (gender, region, primary production, and breed).

Codon 127 142 143 146 154 211 222 240 146, 222
Type of protection Prolonged Incubation Prolonged Incubation Prolonged Incubation Resistance Prolonged Incubation Prolonged Incubation Resistance Prolonged Incubation Resistance
Allele S M R S, D H Q K S S, D, K
Overall proportion 0.3 8.1 14.8 33.3 1.1 5.4 0.6 46.0 33.8
Gender (P value) 0.013 0.081 0.708 0.028 0.600 0.398 0.442 0.392 0.033
Doe 0.3 a 8.4   14.7   34.2 a 1.0   5.6   0.6   45.7   34.7 a
Buck 0.1 ab 5.1   15.8   23.6 ab 1.3   3.6   1.0   49.9   24.4 ab
Region (P value) 0.881 0.232 0.974 0.077 0.034 0.002 0.005 0.135 0.113
West 0.3   6.6   14.8   37.6   0.5 a 2.2 a 0.1 a 43.2   37.7  
East 0.3   9.3   14.8   29.7   1.5 ab 8.1 ab 1.0 ab 48.3   30.7  
Primary production (P value) 0.015 <0.001 <0.001 <0.001 0.415 0.401 0.133 0.240 <0.001
Meat 0.0 a 5.2 a 17.9 a 41.1 a 1.3   5.0   0.6   43.9   41.7 a
Dairy 0.8 ab 20.6 ab 6.7 ab 17.1 ab 0.7   7.3   1.1   49.3   18.2 ab
Other 0.4 ab 4.8 ab 13.9 ab 27.5 a 0.9   4.9   0.1   48.6   27.6 ab
Breed (P value) 0.187 0.003 <0.001 <0.001 0.207 <0.001 0.805 <0.001 <0.001
Alpine 0.0   38.2 abce 0.1 a 3.8 ab 0.1   11.0 abc 0.4   51.2 a 4.2 abc
Angora 0.0   1.2 abcd 0.1 a 0.9 a 0.0   0.0 abcd 0.0   50.7 a 0.9 ab
Boer 0.1   3.5 abcd 26.6 b 47.0 abc 0.5   2.1 abcdef 0.1   51.4 a 47.0 abcd
Cashmere 0.0   0.0 a 17.1 abcd 23.0 abc 0.0   2.0 abcdef 0.0   29.7 a 23.0 abcde
Fainting goats 0.0   7.7 abcd 0.0 a 3.4 abcd 19.7 0.4 abcdefg 0.0   38.8 a 3.4 abcdef
Kiko 0.0   4.9 abcd 18.0 abcd 17.2 abc 1.3   14.6 abc 0.0   46.3 a 17.2 abcde
LaMancha 0.1   13.5 abcd 0.0 a 35.8 abcde 0.0   9.2 abcdef 0.1   31.5 a 35.9 abcde
Nigerian dwarf 0.0   1.3 ab 32.9 ab 0.7 a 0.1   0.8 abcde 0.0   47.0 a 0.7 ab
Nubian 0.2   10.6 abcd 4.7 abcd 38.6 abcde 0.2   0.3 abcdef 0.0   46.6 a 38.6 abcde
Oberhasli 0.0   12.8 abcd 0.4 abc 1.7 ab 0.0   28.5 abc 23.1 95.9 b 24.8 abcde
Pygmy 0.0   0.0 a 27.0 abcde 0.6 ab 0.0   0.0 abcd 0.0   52.8 abc 0.6 abc
Pygora 0.0   0.0 a 0.0 abcdef 1.1 ab 0.0   0.0 abcd 0.0   94.8 abc 1.1 abc
Saanen 1.7   13.8 abcd 0.4 abcd 2.8 ab 2.6   8.1 abcdefg 0.1   33.8 a 2.9 abc
Sable 0.5   56.4 abcde 0.0 abcdef 8.5 abc 0.0   59.7 ab 0.0   85.7 ab 8.5 abcde
Savannah 0.0   15.9 abcde 20.9 abcd 65.5 abcde 0.4   0.0 abcd 0.1   47.2 abc 65.5 abcde
Spanish 0.0   6.0 abcd 11.6 abcde 42.6 abcde 0.8   7.4 abcdef 0.8   35.3 a 43.4 abcdef
Toggenburg 0.0   67.2 abcde 0.6 abcd 13.0 abc 0.0   0.5 abcdef 22.0 29.4 a 35.0 abcde
Crossbred 0.9   9.7 abcd 12.5 abcde 37.7 abcde 2.0   8.4 abc 0.7   48.8 a 38.3 abcde
Other 0.0   8.6 abcd 7.1 abcd 12.3 abbcde 2.3   14.1 abcdef 3.9   53.4 abc 16.2 abcde

Lower case letter coding denotes which levels of a given breakout variable have significantly different proportions of goats with the prolonged incubation or resistant genotypes. Levels that share a letter are not significantly different and levels that do not share a letter are significantly different at the 0.05 significance level with Tukey-Kramer adjustments.