Table 1. Cytotoxicity (IC₅₀) of Juniperus communis (JCo) extract in colorectal cancer cells and normal cells.

Drugs	Colorectal cancer cells		Normal cells
	HT-29	CT-26	MDCK	SVEC
JCo extract
24 h	66.71±0.48.0a,c	27.8±0.2a,b,c	>88.3c	81.1±2.2b,c
48 h	60.02±0.21a,b,c	22.7±0.9a,b,c	>88.3c	74.8±0.3b,c
72 h	54.32±1.58a,b,c	27.3±4.5a,b,c	>88.3b,c	71.2±0.6b,c
5-FU
24 h	>10	2.7±0.03a	>10	6.8±1.3
48 h	1.3±0.4	0.3±0.02a	>10	1.4±0.05
72 h	0.7±0.03	0.4±0.01a	1.1±0.01	0.8±0.03
VP-16
24 h	>100a	44.1±0.4	66.0±1.0	46.2±3.2
48 h	3.3±2.2	9.4±0.03	25.7±2.7	2.2±0.6
72 h	2.3±0.02	4.1±0.1a	2.7±0.2	1.0±0.001

IC₅₀: half maximal inhibitory concentration. Data are reported as means±SD in µg/mL. ^aP<0.05 between tumor cells and normal cells; ^bP<0.05 between JCo extract group and 5-FU treatment group; ^cP<0.05 between JCo extract group and VP-16 treatment group (ANOVA).