Figure 6. Human umbilical vein endothelial cells (HUVECs) were subjected to oxygen-glucose deprivation and reoxygenation (OGD/R) for 4 h prior to engeletin treatment for 24 h, after which western blotting was used to assess protein levels. A and B, Angiogenesis-related protein levels (VEGF, Vash-1, Vash-2). C, Vascular stability-related protein levels (Ang-1, Ang-2, p-Tie2). Data are reported as means±SD (n=3). *P<0.05, **P<0.01 vs OGD/R group; ^##P<0.01 vs normal (N) group (ANOVA with Tukey's test). Vash: vasohibin.