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. 2021 Jul 16;54(10):e11028. doi: 10.1590/1414-431X2020e11028

Table 2. The impact of engeletin on mean cerebral blood flow in cerebral ischemia/reperfusion model rats.

Group Before MCAO MCAO (0 h) 72 h 168 h
Sham 1123.5±150.7 1033.6±134.5 1145.6±169.3 1131.8±201.3
Model 1131.9±127.9 505.6±88.4** 870.5±325.8** 820.4±213.4**
Engeletin, 20 mg/kg 1128.6±122.6 523.66±94.2** 1040.7±342.1## 950.4±265.1##
Axitinib, 10 mg/kg 1178.6±164.6 513.45±85.7** 733.6±257.4** 785.4±112.3**
Axitinib, 10 mg/kg + engeletin 20 mg/kg 1149.3±167.4 510.48±92.5** 893.6±311.6* 860.5±133.2*

Data are reported as means±SD (n=10/group). *P<0.05, **P<0.01 vs sham group; ##P<0.01 vs Model group (ANOVA with Tukey's test).