Table 2.
ROC Curves in Assessing the Statue of Sepsis from the 1st Day to 7th Day
| Variables | Sensitivity (%) | Specificity (%) | AUC (95% CI) | Youden Index |
|---|---|---|---|---|
| TK (Day 1) | 88.00 | 76.74 | 0.878 (0.842–0.908) | 0.647 |
| TK+PCT (Day 1) | 91.64 | 89.15 | 0.948 (0.921–0.967) | 0.808 |
| TK (Day 3) | 67.03 | 80.00 | 0.788 (0.736–0.834) | 0.47 |
| TK+PCT (Day 3) | 80.00 | 79.41 | 0.863 (0.817–0.902) | 0.594 |
| TK (Day 7) | 81.48 | 77.5 | 0.859 (0.811–0.898) | 0.59 |
| TK+PCT (Day 7) | 85 | 81.72 | 0.901 (0.847–0.941) | 0.667 |
Abbreviations: AUC, area under the curve; TK, tissue kallikrein; PCT, procalcitonin; TK+PCT, combination of TK and PCT for assessment of sepsis; Day 1, the first day after clinical onset of sepsis on the ICU; Day 3, 3 days after diagnosis; Day 7, 7 days after diagnosis.