Table 5.
Diagnostic performances of ACR-TIRADS and EU-TIRADS based on different cutoff categories when NIFTP is accepted as a benign pathology
| Malignant (n=57) | Benign (n=194) | SEN (%) | SPE (%) | PPV (%) | NPV (%) | PLR | NLR | |
|---|---|---|---|---|---|---|---|---|
| ACR-TIRADS 1–3 | 13 | 147 | 77 (64–87) | 76 (69–82) | 48 (38–59) | 92 (87–96) | 3.2 (2.4–4.2) | 0.3 (0.2–0.5) |
| ACR-TIRADS 4–5 | 44 | 47 | ||||||
|
| ||||||||
| EU-TIRADS 1–3 | 13 | 155 | 77 (64–87) | 80 (74–85) | 53 (42–64) | 92 (87–96) | 3.8 (2.8–5.3) | 0.3 (0.2–0.5) |
| EU-TIRADS 4–5 | 44 | 39 | ||||||
|
| ||||||||
| ACR-TIRADS 1–4 | 32 | 190 | 44 (31–58) | 98 (95–99) | 86 (68–96) | 86 (80–90) | 21 (8–59) | 0.6 (0.5–0.7) |
| ACR-TIRADS 5 | 25 | 4 | ||||||
|
| ||||||||
| EU-TIRADS 1–4 | 25 | 187 | 56 (42–69) | 96 (93–99) | 82 (66–92) | 88 (83–92) | 16 (7–33) | 0.5 (0.3–0.6) |
| EU-TIRADS 5 | 32 | 7 | ||||||
Data are presented as numbers or percentages. The numbers in parentheses are 95% confidence intervals.
ACR-TIRADS, thyroid imaging reporting and data system of the American College of Radiology; EU-TIRADS, thyroid imaging reporting and data system of the European Thyroid Association; NIFTP, noninvasive follicular thyroid neoplasm with papillary-like nuclear features; SEN, sensitivity; SPE, specificity; PPV, positive predictive value; NPV, negative predictive value; PLR, positive likelihood ratio; NLR, negative likelihood ratio.