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. Author manuscript; available in PMC: 2021 Aug 15.
Published in final edited form as: Neuroimage. 2021 May 27;237:118219. doi: 10.1016/j.neuroimage.2021.118219

Fig. 3. Suppressing the dACC changes RSFC in connections widespread the whole brain.

Fig. 3.

A) Top: averaged ROI-wise RSFC matrices after saline and CNO injections in the all-neuron DREADD group, respectively. Bottom: averaged ROI-wise RSFC matrices after saline and CNO injections in the sham group, respectively. B) Top: connections exhibiting significant RSFC changes after saline and CNO injections (two-way ANOVA, linear mixed model, pinteraction < 0.05, FDR corrected). RSFC changes between the CNO and saline conditions in the DREADD group were color coded with cold colors representing reduced RSFC and hot colors representing increased RSFC. Bottom: Connections with significant functional connectivity changes were grouped into multiple brain systems. Line thickness represents the total number of connections with significant RSFC changes between the two systems.