Table 2.
Effect of pumpkin extract on IL-6, TNF-α, MDA, SOD, GPX, and CAT levels in the serum of the studied groups.
| Parameters | Con | CUMS | CUMS+Flu | CUMS+Pump |
|---|---|---|---|---|
| IL-6 (pg/mL) | 25.9 ± 3.9 | 111.8 ± 11.7 | 64.5 ± 11.9 | 35.4 ± 6.5 |
| P1 < 0.001 | P2 < 0.001 | P2 < 0.001 | ||
|
| ||||
| TNF-α (pg/mL) | 29.6 ± 7.8 | 97.2 ± 11.6 | 52.4 ± 11.7 | 42.7 ± 7.7 |
| P1 < 0.001 | P2 < 0.001 | P2 < 0.001 | ||
|
| ||||
| MDA (nmol/mL) | 1.35 ± 0.14 | 2.23 ± 0.71 | 1.59 ± 0.37 | 1.51 ± 0.18 |
| P1 < 0.001 | P2 = 0.001 | P2 = 0.003 | ||
|
| ||||
| SOD (μ/mL) | 18.92.9 | 9.9 ± 2.1 | 10.5 ± 3.2 | 13.9 ± 3.6 |
| P1 < 0.001 | P2 = 0.62 | P2 = 0.01 | ||
|
| ||||
| GPX (mu/mL) | 58.6 ± 7.8 | 37.5 ± 4.9 | 40.3 ± 12.3 | 47.9 ± 6.9 |
| P1 < 0.001 | P2 = 0.51 | P2 = 0.003 | ||
|
| ||||
| CAT (μ/mL) | 0.41 ± 0.09 | 0.27 ± 0.08 | 0.29 ± 0.09 | 0.37 ± 0.09 |
| P1 = 0.002 | P2 = 0.61 | P2 = 0.03 | ||
P1: significance versus the Con group; P2: significance versus the CUMS group.