Table 3.
Multivariate Analysis (Cox Regression Model) of Significant Factor Associated With Survival at Univariate Analysis
| Factor | Wald | Hazard Ratio (95% Confidence Interval) | Multivariate P Value |
|---|---|---|---|
| Frailty | |||
| Fit (CFS scores 1-3) | 19.649 | Reference | <.001 |
| Vulnerable (CFS scores 4-6) | 7.277 | 6.93 (1.69-28.27) | .007 |
| Frail (CFS scores 7-9) | 11.774 | 12.55 (2.96-53.21) | .001 |
| Sex: male | 8.869 | 1.46 (1.14-1.87) | .003 |
| Age ≥85 y | 1.291 | 1.16 (0.89-1.51) | .26 |
| Severe COVID-19 at ED admission | 13.967 | 1.87 (1.34-2.59) | <.001 |
| CCI comorbidities ≥3 | 6.676 | 1.54 (1.11-2.13) | .010 |
| Dependent in ADL | 1.333 | 1.24 (0.86-1.80) | .25 |
| Dementia | 0.015 | 1.02 (0.77-1.35) | .90 |
| Delirium in ED | 1.698 | 0.79 (0.56-1.12) | .19 |
ADL, activities of daily living; CCI, Charlson Comorbidity Index; ED, emergency department; NEWS, National Early Warning Score.
Cutoff values for continuous variables were chosen according to receiver operating characteristic (ROC) curve analysis Youden index J. Time was calculated from ED admission to discharge/death.