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. 2021 Apr;132(4):904–913. doi: 10.1016/j.clinph.2021.01.009

Table 5.

Electrocardiogram (ECG) metrics for REM sleep behaviour disorder (RBD) detection, which aimed to capture changes in heart rate variability during sleep.

Channel Category Description Reference
ECG Time The mean RR interval standard deviation during all REM epochs (RR_REM_Std), (Andreotti et al., 2018)
ECG Frequency The mean RR interval low frequency peak during NREM epochs (LFpeak_NREM), mean RR interval low frequency peak during REM epochs (LFPeak_REM), mean RR interval high frequency peak during NREM epochs (HFpeak_NREM), and the RR interval high frequency peak during REM epochs (HFPeak_REM). (Andreotti et al., 2018)
ECG Non-linear The mean sample entropy during REM (SampEn_REM). (Andreotti et al., 2018)
ECG Heart beat regularity The mean irregular index (IrrIndex_NREM), the mean irregular index calculated for each REM epoch (IrrIndex_REM), the mean origin count for all NREM epochs (OriginCount_NREM), and mean origin count for all REM epochs (OriginCount_REM) (Sarkar et al., 2008)
ECG RR index The mean RR interval ratio between REM and NREM epochs (RR_Index). This work
ECG LFHF ratio The mean RR interval low frequency to high frequency ratio between NREM and REM epochs (LFHF_Index). This work
NA NREM ratio Ratio of NREM sleep compared to REM sleep (Ratio_NREM). This work