Table 3:
Percent change, p-values, and 95% confidence intervals for ANCOVA group comparisons. Mean cerebellar metabolic values with standard deviations are also reported. LOTS patients drove most of the significant metabolic differences. All p-values are un-adjusted but are corrected for multiple comparisons and noted in bold.
| Cerebellum Metabolic Values |
NAA | mI | Glx | Cr | Cho |
|---|---|---|---|---|---|
| % Change p-values [95% CI] | |||||
| 10 LOGG vs. 7 CTRL | −20.0% 0.015 [0.3657, 2.4934] |
26.7% 0.043 [0.1005, 3.0279] |
−16.9% 0.065 [−0.0570, 4.2779] |
−5.6% 0.14 [−0.1778, 1.1582] |
−5.8% 0.071 [−0.0064, 0.2423] |
| 7 LOTS vs. 7 CTRL | −28.2% 0.0003* [1.093, 2.923] |
38.7% 0.0064* [0.8773, 3.6513] |
−25.6% 0.0018* [1.4071, 4.9871] |
−10.0% 0.0065* [0.3354, 1.4062] |
−6.3% 0.12 [−0.0257, 0.2759] |
| Concentration (mean± SD) | |||||
| LOGG Patients | 5.71±1.24 | 7.40±1.67 | 10.41±2.59 | 8.20±0.71 | 1.96±0.10 |
| LOTS Patients | 5.13±0.99 | 8.10±1.48 | 9.32±2.04 | 7.82±0.41 | 1.95±0.12 |
| LOSD Patients | 7.06±0.26 | 5.77±0.58 | 12.94±2.00 | 9.09±0.27 | 1.98±0.07 |
| Controls | 7.14±0.50 | 5.84±0.81 | 12.52±0.74 | 8.69±0.51 | 2.08±0.14 |
Denotes regions significant after FDR multiple comparisons corrections