Fig. 2.

Lower mitochondrial content in PE placentae. Mitochondrial DNA copy number (a), citrate synthase activity (b), and mRNA transcript levels of COXII (c) were assessed in PE as well as control placentae. Data is presented as fold change compared to the control placentae and as mean with SEM from n = 11 (controls), n = 12 (preeclampsia) for assessment of mRNA levels and n = 9 (controls), n = 8 (preeclampsia) for the assessment of CS activity and mtDNA copy number. *p ≤ 0.05 and **p ≤ 0.01. mtDNA, mitochondrial DNA; CS, citrate synthase; COXII, cytochrome c oxidase subunit II