Table 1.

Subject characteristics.

	CD n = 65	UC n = 107	IBS n = 18	HS n = 20
Age
Mean (range)	36.32 [18–76]	45.20 [18–80]	39.0 [21–71]	40.6 [19–68]
Sex
Males (%)	36 [55.4]	62 [57.9]	13 [72.2]	12 [60]
Females (%)	29 [44.6]	45 [42.1]	5 [27.8]	8 [40]
Smoking
Current (%)	19 [29]	9 [8]	2 [11]	1 [5]
Former (%)	17 [26]	48 [45]	3 [17]	5 [25]
Never (%)	28 [43]	50 [47]	13 [72]	14 [70]
BMI	25 [16–51]	26 [17–56]	24 [19–37]	26 [19–44]
Disease duration	6.7 [0–38]	8.3 [0.1–39]
Treatmenta
5-ASA, topical	0 [0]	30 [28]
5-ASA, oral	7 [11]	71 [66]
Corticosteroids, topical	0 [0]	2 [2]
Corticosteroids, oral	4 [6]	7 [6]
Corticosteroid, iv	2 [3]	3 [3]
Immunosuppressant	23 [35]	18 [17]
Biologic agents	39 [60]	22 [21]
No treatment	6 [9]	12 [11]
Clinical disease activity
HBI (remission/mild/moderate/severe) (n = 65)	41/13/10/1
Mayo partial (remission/mild/moderate/severe) (n = 107)		52/23/28/4
Endoscopic disease activity
SES-CD (remission/mild/moderate/severe) (n = 17)	7/3/5/2
Mayo endo (remission/mild/moderate/severe) (n = 63)		11/21/20/11
Montreal classification CD
Age at diagnosis (A1/A2/A3) (n = 65)	10/46/9
Location (L1/L2/L3/L4) (n = 65)	10/24/31/0
Behavior (B1/B2/B3) (n = 65)	38/19/8
Montreal classification UC
Disease extension (E1/E2/E3) (n = 107)		34/47/26

HBI: remission (< 5), mild (5–7), moderate (8–16), severe (> 16). Mayo partial: remission (< 2), mild (2–4), moderate (5–7), severe (> 7). SES-CD: Simple endoscopic score of Crohn’s disease: remission (0–2), mild (3–6), moderate (7–15), severe (> 15). Mayo endo: remission (0), mild (1), moderate (2), severe (3). A1: below 16 years, A2: between 17 and 40 years, A3, above 40 years. L1: ileal, L2: colonic, L3: ileocolonic, L4: isolate upper disease. B1: non-stricturing, non-penetrating, B2: stricturing, B3: penetrating. E1: proctitis, E2: Left sided, E3: extensive.

CD Crohn’s disease, UC ulcerative colitis, IBS irritable bowel syndrome, HS healthy subjects.

^aSome patients received more than one treatment.