Table 1.

Performance of therapy-based stratification.

Therapy	Yes-no-yes	No-no-yes	No-no-no	Yes-no-no	Yes-yes-yes
n.p.	43	31	21	13	35
$>5y$	17	14	7	8	8
$<5y$	26	17	14	5	27
n.a.	37	30	21	13	30
Sen.	0.65	0.81	0.66	0.85	0.8
Spec.	0.92	0.78	0.8	0.66	0.84
OR	24.3	16.8	8.0	12.0	21.0
OR p-val	0.0006	0.002	0.11	0.1	0.01
CI-Lo	2.6	2.55	0.96	0.79	1.8
CI-Hi	221	111	66	180	240
Kappa	0.52	0.58	0.44	0.53	0.51
AUC	0.85	0.87	0.77	0.77	0.63
AUC p-val	0.0001	0.0002	0.02	0.06	0.13
lrt p-val	0.02	0.0006	0.06	0.33	0.03
lh	2	2	4	1	3
fp	7	12	17	8	5

Results on test data with automatic hyperparameter optimization and feature (gene) selection. Therapy class labels are (RAD, CHE, HOR). n.p. number of patients, n.a. number of answers. 95% confidence interval, lrt p-val p value for the log rank test, lh lookahead number, fp fingerprint size.