Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 6;14:706494. doi: 10.3389/fnmol.2021.706494

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Badawi, Mori, Kurihara, Yoshizawa, Nohara, Kouyama-Suzuki, Yanagawa, Shirai and Tabuchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Administration of risperidone ameliorated increased repetitive behaviors but not social deficits in SIK1-MT mice. (A) Total travel distance of saline (Sal)- and risperidone (Ris)-injected SIK1-MT mice. (B) The percentage of the time spent in the center of the open field arena. (C) Total time of the vertical activities of saline (Sal, n = 10) and risperidone (Ris, n = 9) -injected SIK1-MT mice. (D) The number of groomings during the observation period. (E) The number of marbles buried in the marble burying test. The number of buried marbles was less in risperidone-injected SIK1-MT mice compared to that of saline-injected. (F,G) Sociability and the social novelty test between saline- and risperidone-injected SIK1-MT mice. Risperidone did not affect social behavior in SIK1-MT mice. The numbers of neurons and mice used in each analysis are shown on the bar (neurons/mice) in the graphs. Statistical analysis was made by Student's t-test. Statistical significance was indicated by asterisks (*p < 0.05 and **p < 0.01).