Table 3.
Multivariable analysis relating adherence metrics to 6 month outcomes.
| Six-month outcomes (adjusted for age, sex, peripheral blood eosinophils and FEV1) | |||||
|---|---|---|---|---|---|
| Adherence metric | Outcome measure at 6 months | Coefficient [SE] (p value) when adjusted for | |||
| Age | Sex | Blood Eosinophils | FEV1 | ||
| Entropy (H) | Attacks requiring hospitalisation |
1·35 [0·68] (p = 0·046) |
1·34 [0·68] (p = 0·047) |
2·37 [1·50] (p = 0·113) |
1·4 [0·69] (p = 0·044) |
| Decreasing Entropy (Hdec) | Attacks requiring GP visit |
0·98 [0·49] (p = 0·045) |
0·98 [0·43] (p = 0·021) |
0·91 [0·48] (p = 0·059) |
1·03 [0·43] (p = 0·017) |
| Attacks requiring oral corticosteroids |
0·83 [0·39] (p = 0·034) |
0·91 [0·38] (p = 0·017) |
0·50 [0·46] (p = 0·284) |
0·99 [0·40] (p = 0·014) |
|
| Attacks requiring hospitalisation |
1·11 [0·60] (p = 0·064) |
1·07 [0·59] (p = 0·068) |
0·82 [0·69] (p = 0·231) |
1·10 [0·58] (p = 0·058) |
|
GP general practitioner. Adherence metrics and outcome measures reported here are those which showed significant associations in univariate analyses.