Table 4.
Sex-stratified, multivariable Cox regression analysis with HR for incident DD in relation to ApoA1, ApoB and the ApoB/ApoA1 ratio, adjusted for age at baseline, hypertension, DM, alcohol consumption, BMI, manual work, and smoking.
| Variable | HR (95% CI)a | p-value |
|---|---|---|
| Men | ||
| ApoA1 | 1.22 (1.09–1.38) | < 0.01 |
| ApoB | 0.97 (0.86–1.09) | = 0.64 |
| ApoB/ApoA1 | 0.85 (0.75–0.96) | = 0.01 |
| Women | ||
| ApoA1 | 1.17 (1.01–1.36) | = 0.03 |
| ApoB | 0.83 (0.70–0.99) | = 0.03 |
| ApoB/ApoA1 | 0.80 (0.66–0.97) | = 0.02 |
BMI body mass index, CI confidence interval, DD Dupuytren’s disease, HR Hazard Ratio. Bold values indicating p < 0.05.
aHR are expressed as per one SD increase of respective Z-score converted variable.