Table 3.

ADME profile prediction of the phytosterols from Lagerstroemia speciosa

	L1	L2	L3	L4
Log S	− 5.42	− 6.9	− 5.71	− 4.7
Solubility class	Insoluble	Poorly soluble	Poorly Soluble	Poorly soluble
Absorption
BBB	BBB + (0.9676)	BBB + (0.9391)	BBB + (0.9841)	BBB + (0.9743)
HIA	HIA + (1.0)	HIA + (0.9961)	HIA + (1.00)	HIA + (1.00)
Caco-2	caco2 + (0.7337)	caco2 + (0.5872)	caco2 + (0.6658)	caco2 + (0.7953)
Distribution
p-glyco substrate	Substrate	Substrate	Substrate	Substrate
p-glyco Inhibitor	Inhibitor	Inhibitor	Inhibitor	Inhibitor
ROCT	Non-Inh	Non-Inh	Non-Inh	Non-Inh
Metabolism
2C9 SUB	Non-sub	Non-sub	Non-sub	Non-sub
C2DR SUB	Non-sub	Non-sub	Non-sub	Non-sub
3A4 SUB	Substrate	Substrate	Substrate	Substrate
1A2 INH	Non-Inh	Non-Inh	Non-Inh	Non-Inh
2C9 INH	Non-Inh	Non-Inh	Non-Inh	Non-Inh
2DR INH	Non-Inh	Non-Inh	Non-Inh	Non-Inh
2C19 INH	Non-Inh	Non-inh	Non-Inh	Non-Inh
3A4 INH	Non-Inh	Non-Inh	Non-Inh	Non-Inh