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. 2021 Jul 19;6:63. doi: 10.1038/s41525-021-00224-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Recommended diagnostic algorithm for patients presenting with potential incidental findings identified through NGS-MGP testing on peripheral blood leukocyte (PBL)-derived DNA. Genetic findings in individuals undergoing germline NGS-MGP testing on PBLs are classified in one of three categories and subsequently undergo further testing to identify downstream surveillance and diagnosis. This includes secondary tissue analysis (culture skin biopsy preferred) and medical chart review. CBC complete blood count.