Table 1.
Clinico-demographic and imaging variables in healthy volunteer (HV) and schizophrenia (SCZ) groups. Values are mean (SEM) or number (n).
| HV | SCZ | t | Kolmogorov-Smirnov D | Chi-square | df | p | |
| Age (years) | 38.23 [2.59] | 40.89 [2.75] | – | 0.25 | – | – | 0.55 |
| Male; Female (n) | 21; 1 | 15; 3 | – | – | 1.62 | – | 0.20 |
| Ethnicity | |||||||
| White; black; other (n) | 9; 9; 4 | 3; 13; 2 | – | – | 4.03 | 2 | 0.13 |
| Current smoker (n) | 3 | 12 | – | – | 11.88 | 1 | 0.0006 |
| Cannabis use within last month (n) | 0 | 2 | – | – | 2.57 | 1 | 0.11 |
| Activity injected | 264.40 [5.62] | 243.60 [10.88] | – | 0.32 | – | – | 0.25 |
| Plasma free fraction | 0.24 [0.005] | 0.24 [0.005] | 0.82 | – | – | 38.0 | 0.42 |
| CS | |||||||
| [11C]UCB-J VT | 5.62 [0.12] | 5.92 [0.34] | 0.91 | – | – | 38.0 | 0.37 |
| ACC | |||||||
| [11C]UCB-J DVR | 3.95 [0.10] | 3.48 [0.18] | 2.38 | – | – | 38.0 | 0.02 |
| [11C]UCB-J VT | 22.08 [0.67] | 19.19 [0.76] | 2.87 | – | – | 38.0 | 0.007 |
| Glu/Cr | 1.10 [0.02] | 1.06 [0.02] | 1.35 | – | – | 38.0 | 0.19 |
| Glx/Cr | 1.29 [0.03] | 1.31 [0.05] | 0.31 | – | – | 38.0 | 0.75 |
| NAA/Cr | 1.13 [0.02] | 1.14 [0.02] | 0.04 | – | – | 38.0 | 0.97 |
| Left hippocampus | |||||||
| [11C]UCB-J DVR | 2.67 [0.08] | 2.46 [0.14] | 1.42 | – | – | 38.0 | 0.17 |
| [11C]UCB-J VT | 14.92 [0.50] | 14.17 [0.54] | 1.00 | – | – | 38.0 | 0.32 |
| Glu/Cr | 0.97 [0.03] | 0.93 [0.04] | 0.78 | – | – | 37.0 | 0.44 |
| Glx/Cr | 1.38 [0.06] | 1.28 [0.07] | 1.03 | – | – | 37.0 | 0.31 |
| NAA/Cr | 1.10 [0.03] | 1.07 [0.04] | 0.71 | – | – | 37.0 | 0.48 |