Skip to main content
. Author manuscript; available in PMC: 2021 Jul 20.
Published in final edited form as: Bioorg Med Chem Lett. 2019 Feb 26;29(9):1113–1119. doi: 10.1016/j.bmcl.2019.02.027

Figure 3.

Figure 3.

The activity of 32 on viral titer. Triplicate cultures were infected with A/PR/8/34 at a MOI of 0.1 and treated with the indicated concentrations of compound. After 48 h (time), the supernatants were collected and analyzed to determine the reduction in virus by assaying the supernatant infectivity. The data are presented (left) as a percent decrease in titer back-calculated from TCID50S where IC90 is 155 nM and (right) the actual TCID50s where 3 log units of viral suppression are observed at 1.6 μM concentration.