TABLE 2.

Multivariate analysis for a mutually exclusive triple of overall survival in the cohort (KEAP1 subtype two–FAT3 subtype one–EGFR subtype one)

Variables		Univariate			Multivariate
	HR	95% CI	p value	HR	95% CI	p value
Age	1.009	0.994–1.025	0.249	1.010	0.994–1.026	0.237
AJCC stage
Stage II versus I	2.345	1.624–3.388	<0.001*	0.998	0.527–1.890	0.995
Stage III versus I	3.495	2.379–5.133	<0.001*	1.110	0.429–2.877	0.829
Stage IV versus I	3.341	1.834–6.088	<0.001*	1.641	0.746–3.607	0.218
T stage
T2 versus T1	1.409	0.984–2.018	0.061	1.264	0.866–1.843	0.224
T3 versus T1	3.027	1.798–5.097	<0.001*	2.446	1.299–4.607	0.006*
T4 versus T1	3.117	1.641–5.920	<0.001*	2.062	0.948–4.484	0.068
N stage
N1 versus N0	2.363	1.669–3.346	<0.001*	2.127	1.176–3.846	0.013*
N2 versus N0	3.115	2.123–4.569	<0.001*	2.274	0.975–5.302	0.057
N3 versus N0	3.842	0–Inf	0.994	2.570	0–Inf	0.994
Gender
Male versus Female	1.05	0.779–1.416	0.747	0.951	0.695–1.302	0.755
KEAP1 subtype two–FAT3 subtype one–EGFR subtype one
Mutations versus wild type	1.573	1.144–2.163	0.005*	1.440	1.023–2.027	0.036*

Significant p values are labeled with *(p < 0.05).