Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Stepwise covariate analysis of the genetic polymorphisms
| Polymorphism | Pharmacokinetic variable | OFV | p‐value |
|---|---|---|---|
| Base model | −758.44 | ||
| CYP3A4*1B | Cl (L/h) | −758.78 | 0.84 |
| CPP3A5*3 | Cl (L/h) | −759.364 | 0.63 |
| ABCBI | |||
| C1236GT | Cl (L/h) | −760.986 | 0.28 |
| V3 (L) | −760.656 | 0.33 | |
| C3435T | Cl (L/h) | −758.58 | 0.93 |
| V3 (L) | −761.58 | 0.20 | |
| G2677T | Cl (L/h) | −758.69 | 0.88 |
| V3 (L) | −761.85 | 0.18 | |
| SLCOIB1 | |||
| G1187A | Cl (L/h) | −759.78 | 0.51 |
| V3 (L) | −760.20 | 0.41 | |
Abbreviation: OFV, objective function value.
