Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Prediction performance for mutated genes with a prevalence of more than 10%
| Gene mutation | Logistic regression AUC | Positive cases (n = 290) |
|---|---|---|
| FGFR3 | 0.85 | 53 (18%) |
| TP53 | 0.72 | 139 (48%) |
| RB1 | 0.57 | 75 (26%) |
| PIK3CA | 0.55 | 60 (21%) |
| CREBBP | 0.48 | 38 (13%) |
| CDKN2A | 0.46 | 112 (39%) |
| CCND1 | 0.44 | 36 (12%) |
| CDKN2B | 0.37 | 95 (33%) |
| RAF1 | 0.36 | 32 (11%) |
| E2F3 | 0.30 | 49 (17%) |
| ERBB2 | 0.21 | 37 (13%) |
| FGFR2/FGFR3 mutation | 0.74 | 55 (19%) |
Abbreviation: AUC, area under the curve.
