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. 2021 Jul 6;12:693440. doi: 10.3389/fneur.2021.693440

Table 1.

Frequencies of MS onset symptoms (%) in the Swiss Multiple Sclerosis Registry; overall, by sex and by MS type; p-values after χ2-test.

Sex MS type
All Men Women P-value PP RR SP P-value
Balance problems 575 (28.6) 160 (28.8) 415 (28.2) 0.564 71 (34.1) 387 (28.0) 106 (27.5) 0.166
Bladder problems 225 (11.1) 59 (10.8) 166 (11.2) 0.788 30 (14.0) 144 (10.4) 46 (11.8) 0.252
Bowel problems 185 (9.2) 37 (6.8) 148 (10.0) 0.026 25 (11.7) 125 (9.0) 35 (9.1) 0.442
Depression symptoms 247 (12.2) 61 (11.2) 186 (12.6) 0.406 28 (13.0) 171 (12.4) 43 (11.1) 0.730
Dizziness 423 (20.8) 102 (18.7) 321 (21.6) 0.156 30 (14.0) 319 (23.0) 66 (17.0) 0.001
Epilepsy 21 (1.0) 5 (0.9) 16 (1.1) 0.746 2 (0.9) 15 (1.1) 3 (0.8) 0.860
Fatigue 707 (35.2) 163 (29.4) 544 (37.1) 0.004 81 (38.9) 510 (37.0) 107 (27.9) 0.003
Gait problems 642 (31.7) 196 (35.9) 446 (30.2) 0.014 115 (53.7) 376 (27.1) 137 (35.5) 0.000
Memory problems 174 (8.6) 40 (7.3) 134 (9.0) 0.216 18 (8.4) 130 (9.4) 21 (5.4) 0.043
Pain 286 (14.1) 66 (12.0) 220 (14.9) 0.104 36 (16.7) 200 (14.4) 44 (11.3) 0.154
Paralysis 526 (26.0) 141 (25.8) 385 (26.0) 0.925 60 (27.9) 355 (25.6) 102 (26.5) 0.755
Paresthesia 1,194 (58.8) 307 (56.2) 887 (59.7) 0.155 94 (44.1) 851 (61.2) 226 (57.9) 0.000
Sexual problems 121 (6.0) 42 (7.7) 79 (5.3) 0.045 21 (9.8) 71 (5.1) 26 (6.7) 0.020
Spasms 188 (9.3) 55 (10.1) 133 (9.0) 0.444 42 (19.6) 106 (7.6) 34 (8.8) 0.000
Speech problems 137 (6.7) 40 (7.3) 97 (6.5) 0.545 9 (4.2) 105 (7.6) 19 (4.9) 0.050
Swallowing problems 53 (2.6) 16 (2.9) 37 (2.5) 0.594 8 (3.7) 34 (2.4) 10 (2.6) 0.581
Tics 87 (4.3) 26 (4.7) 61 (4.1) 0.518 11 (5.1) 56 (4.0) 19 (4.9) 0.646
Tremor 117 (5.7) 29 (5.3) 88 (5.9) 0.584 13 (5.9) 81 (5.8) 21 (5.4) 0.943
Vision problems 829 (40.8) 200 (36.6) 629 (42.3) 0.021 62 (28.6) 572 (41.1) 184 (47.5) 0.000
Weakness 638 (31.6) 159 (29.2) 479 (32.5) 0.164 78 (37.0) 427 (30.9) 122 (31.6) 0.208