Table 2.

GcgR antagonist partially improved the survival of diabetic mice subjected to CLP.

Group	Dead/Total	Survival (%)
Sham non-diabetic	0/10	100
CLP non-diabetic	0/10	100
Sham diabetic	0/7	100
CLP diabetic	5/10	50&
CLP diabetic + GcgR Ant (1 mg/Kg, i.p.)	3/10	70

CLP was performed 21 days after alloxan-induced-diabetes, and the treatment with GcgR antagonist (1 mg/Kg, i.p.) was carried out 24h and 1h before CLP. The survival rate was evaluated from 0 to 24h after induction of sepsis through CLP. CLP, Cecum ligation and puncture; GcgR Ant, GcgR Antagonist. ^& P < 0.05 compared to CLP non-diabetic group.